Endocrine Abstracts

Introduction: In addition to the medication prescribed by their doctors, patients may recourse to natural medicine and take herbal medications without thinking about their potential side effects and interactions with other drugs.Case Report: A 39-year-old female, with personal history of iron deficiency anemia, regular menses but long-standing dysmenorrhea and polymenorrhea and reactive anxiety-depressive disorder, complained of frequent intermenstrual s...

Background: Insulin-related peptides are found in Cnidaria (the most ancient animals with differentiated tissues including a nervous system, dating from 600 million years ago) and their nucleotide sequence has been highly preserved ever since. In mammals the binding of insulin to its receptor causes a cascade of actions, the main one being translocation of GLUT4 glucose transporters to the plasma membrane allowing influx of glucose into the adipose and striated muscle cells. B...

Introduction and objectives: Testosterone therapy (TT) in female-to-male transsexuals (FMT) usually causes cessation of menses within the first few months. However the changes in the hormonal profile are not well known. We set out to analyze the hormonal changes and menstrual evolution in a cohort of FMT who began TT.Methodology: Retrospective observational study with no control group in a cohort of 34 FMT patients who started TT following a standard pro...

Introduction: While iatrogenic Cushing’s syndrome is common, acquired isolated ACTH deficiency is a rare condition. Hypophysitis is the most common cause, and while most recently published cases are associated with immunotherapy, it may also be idiopathic. Hereby we present a case of cortical adrenal atrophy secondary to idiopathic acquired ACTH deficiency, in order to raise awareness about this condition.Material and Methods: Review of the patient&...

A 27-year-old male without relevant familial or personal history had three TIAs in the last year, lasting for about 20 min with partial right palsy and aphasia. By the time he was cared for in the Emergency Department. he had already recovered; his lab tests, chest X-ray and EKG were normal but his BP was high (PAS 170–190 mmHg, PAD 105–120 mmHg). He had no chest pain, headache or neurovegetative symptoms. On discharge the patient was treated with manidipine and ASA ...

Objectives: Understanding and propagating the knowledge of the burden caused by the massive infradiagnosis of Primary Aldosteronism (PA), partly due to unawareness of its high prevalence and partly to the complexity of its screening in Primary Care and workup in Specialized Care.Methods: Review of the relevant literature and personal reflections.Results: PA is the first cause of secondary hypertension and a highly prevalent disease...